Abuse Liability of Reduced Nicotine Content Cigarettes Within a Complex Tobacco Marketplace

• Status: Completed
• Trial end date: 2019-11-01
• Target enrollment: 0
• Participant gender: All

Summary

Tobacco regulatory policies can have unanticipated consequences; therefore, methods that would permit prospective estimates of the effects of potential tobacco regulations are necessary for the development of tobacco regulatory science. The goal of this project is to experimentally assess how smokers purchase and consume reduced-nicotine cigarettes. In experiment 1, we will investigate how purchasing/consuming reduced-nicotine cigarettes is related to nicotine content and absorption. In experiment 2, we will investigate how purchasing/consuming changes when other nicotine products are available in an experimental marketplace setting. The proposed projects can directly inform tobacco regulation by providing estimates of the real-world effects of novel policies.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Virginia Polytechnic Institute and State University
• Collaborator: University of Kentucky
• Treatments: Nicotine

Criteria

Inclusion Criteria:

• smoke at least 5 cigarettes per day

• have a breath carbon monoxide (CO) level of at least 10 ppm at intake

• no immediate plans to quit smoking.

Exclusion Criteria:

• pregnant, lactating, plans to become pregnant

• weigh more than 110lbs (experiment 1 only)

• have plans to move out of the area during the course of the experiment

To see if you are eligible, use the following confidential link:

http://vtcri.info/arrcclinicaltrials