Abuse Potential of Buprenorphine and Naloxone in Non-Dependent Opioid Users

• Status: Completed
• Trial end date: 1998-03-01
• Target enrollment: 0
• Participant gender: All

Summary

Buprenorphine is a medication used to treat opioid addiction, but individuals who use this drug are at risk of abusing it. A buprenorphine and naloxone combination may reduce the likelihood of buprenorphine addiction. This study will evaluate the potential for abuse of buprenorphine and a buprenorphine and naloxone combination in non-dependent opioid users.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: National Institute on Drug Abuse (NIDA)
• Treatments: Buprenorphine; Hydromorphone; Naloxone

Criteria

Inclusion Criteria:

• Current opioid abuse

• Not physically dependent on opioids

Exclusion Criteria:

• Significant medical or psychiatric illness (e.g., insulin-dependent diabetes or schizophrenia)

• Seeking substance abuse treatment (will be assisted with referrals to community-based treatment programs)

• Pregnant