Overview

Accelerated Development of Additive Pharmacotherapy Treatment (ADAPT-2) for Methamphetamine Use Disorder

Status:
Completed
Trial end date:
2019-07-25
Target enrollment:
Participant gender:
Summary
This is a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy of extended-release naltrexone plus bupropion as a combination pharmacotherapy for methamphetamine use disorder. Participants will be randomly assigned to the active medication combination (AMC) group or matching placebo group and will receive medications over the course of 12 weeks. Follow-ups will occur in weeks 13 and 16.
Phase:
Phase 3
Details
Lead Sponsor:
University of Texas Southwestern Medical Center
Collaborators:
National Institute on Drug Abuse (NIDA)
The Emmes Company, LLC
The EMMES Corporation
Treatments:
Bupropion
Methamphetamine
Naltrexone