Acceleration of Insulin Action by Hyaluronidase During Closed-Loop Therapy
Status:
Completed
Trial end date:
2016-07-01
Target enrollment:
Participant gender:
Summary
"Closed loop artificial pancreas" systems have been under development for the control of
blood sugars in those living with diabetes. These systems consist of a continuous glucose
sensor, which sends a signal to a computer program that automatically determines how much
insulin to give. The computer program then tells an insulin pump to deliver the insulin.
While such systems have been tested under a number of conditions, post-meal blood sugars are
difficult to control. Specifically, we will be looking to see if using hyaluronidase improves
the ability of the closed loop artificial pancreas to better respond to meal related highs
and lows.