Accurate Screening Tools for Dysphagia in Amyotrophic Lateral Sclerosis (ALS)

• Status: Completed
• Trial end date: 2017-12-19
• Target enrollment: 0
• Participant gender: All

Summary

Individuals with th Amyotrophic Lateral Sclerosis are at high risk for swallowing impairment (dysphagia) which leads to malnutrition, decreased pulmonary health, aspiration and aspiration pneumonia. These sequelae necessitate timely identification of at risk individuals to ensure optimal management of oral intake and pulmonary function. The purpose of this study is to evaluate the discriminant ability of several non-invasive screening tools at detecting swallowing impairment in individuals with ALS.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Florida
• Treatments: Capsaicin

Criteria

Inclusion Criteria:

• diagnosis of probable or definite ALS

Exclusion Criteria:

• allergies to barium or capsaicin

• tracheotomy or mechanical ventilation

• absence of diaphragmatic pacer

• respiratory disease (COPD).