Acetaminophen Versus IV Hydromorphone for Pain in the Elderly in the ED
Status:
Active, not recruiting
Trial end date:
2022-03-23
Target enrollment:
Participant gender:
Summary
Intravenous opioids are the mainstay of acute, severe pain treatment in Emergency Departments
(ED) across the country. Acetaminophen, given orally, has also been used for treatment of
mild to moderate pain. The more potent intravenous (IV) form of acetaminophen has been widely
used in Europe for more than 20 years as post-surgical analgesia and received full FDA
approval in the USA in 2010. As part of a continuing set of studies whose goal is to optimize
treatment of pain among elderly ED patients, this randomized study will compare efficacy and
safety of IV acetaminophen to IV hydromorphone.