Acetaminophen Versus Ibuprofen for the Control of Immediate and Delayed Pain Following Orthodontic Separator Placement

• Status: Completed
• Trial end date: 2008-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this research study is to compare pain control effectiveness of two medicines and a placebo (a dummy pill that does not contain any pain relieving medication) to see which one works better at preventing pain when taken both 1 hour before and 6 hours after orthodontic separators are placed. The research hypothesis is that there will be a significant difference in pain as measured by Visual Analogue Scales (VAS) over time and that this effect will differ for acetaminophen versus ibuprofen.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Missouri, Kansas City
• Treatments: Acetaminophen; Ibuprofen

Criteria

Inclusion Criteria:

• Orthodontic treatment requires banding of posterior teeth

• Orthodontic treatment requires the placement of two or more separators

• Able to swallow analgesic pills

• English speaking

• Age 9-17

• Minimum weight requirement of 88 pounds

Exclusion Criteria:

• Orthodontic appliances are present in the mouth

• Use of acetaminophen or ibuprofen is contraindicated (allergy, GI problems)

• Antibiotics or analgesics are currently in use

• History of systemic disease exists (arthritis, diabetes, cystic fibrosis)

• Significant cognitive impairment