Acetaminophen vs Placebo in the Pre-operative Setting and Outcomes on Post-operative Pain, Nausea and Vomiting

• Status: Terminated
• Trial end date: 2017-05-03
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to determine whether a single dose of IV acetaminophen can improve post-operative pain, nausea, and vomiting in the outpatient setting. Patient satisfaction, time to readiness of discharge, and the amount of opiates post operatively will also be measured.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Catholic Health Initiatives; MercyOne Des Moines Medical Center
• Treatments: Acetaminophen

Criteria

Inclusion Criteria:

Each of the following must be met:

• Greater than or equal to 18 years of age.

• Female

• Undergoing outpatient breast surgery (unilateral or bilateral surgery)

Exclusion Criteria:

If ANY of the following apply:

• History of an allergy or hypersensitivity to acetaminophen (oral, rectal, or IV)

• Chronic alcoholism

• Severe deficiency of liver and/or kidney

• Any patient unable to sign informed consent

• Pregnancy

• Any patient currently enrolled in another experimental protocol