Acetated Ringer´s Solution in Experimental Hypovolemia
Status:
Not yet recruiting
Trial end date:
2024-07-29
Target enrollment:
Participant gender:
Summary
Intravenous fluids are often given to increase stroke volume and thereby improve global
oxygen delivery. The effect is however often transient, but the effect of a fluid bolus on
stroke volume and other hemodynamic variables over time are poorly described. The volume
effect of a fluid bolus (effect on blood volume) can be calculated by measuring Haemoglobin.
The purpose of this study is to elucidate the hemodynamic effects of a fluid bolus during
normovolemia and hypovolemia in healthy volunteers. Study details include:
• Study Duration: 2 visits of approximately 2 h duration each + follow-up visit. Visits 1 and
2 are at least 2 days apart. Number of Participants: A maximum of 15 participants will be
enrolled to study intervention such that 12 evaluable participants complete the study