Acetazolamide in Decompensated Heart Failure With Volume OveRload (ADVOR)
Status:
Recruiting
Trial end date:
2022-02-01
Target enrollment:
Participant gender:
Summary
This clinical research study is being conducted in multiple hospitals in Belgium and
approximately 519 patients with acute decompensated heart failure are expected to
participate. Large-scale research shows that 90% of the physicians treat volume overload with
high doses of loop diuretics. However, there is not a lot of scientific data available
regarding the optimal doses of these diuretic medications. In addition, it is observed that a
lot of people, treated with these drugs, are being readmitted to the hospital due to a new
episode of heart failure. The hypothesis of this study is that the volume overload could be
better treated when patients receive a combination of different types of diuretics.
Additionally, the total dose of the administrated diuretics might be lower this way.