Acoustic Assessment of Nebulized Epinephrine Versus Albuterol for RSV Bronchiolitis- a Double Blind Study

• Status: Terminated
• Trial end date: 2001-05-01
• Target enrollment: 0
• Participant gender: All

Summary

Bronchiolitis is a common disease of infancy and a main reason for infants' hospital admissions in the first 2 years of life. The main cause of bronchiolitis is RSV (respiratory syncytial virus). Though, Treatment is mainly supportive, the treatment benefit of nebulized epinephrine or albuterol has been largely debated for the past years. Most of the clinical studies used clinical parameters to detect and compare the effectiveness of such medical interventions. In this study we will use non invasive computerized method of wheeze and crackles quantification to compare the effectiveness of nebulized epinephrine vs albuterol in RSV Bronchiolitis.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Rambam Health Care Campus
• Treatments: Albuterol; Epinephrine; Epinephryl borate; Racepinephrine

Criteria

Inclusion Criteria:

• Under one year of age

• first episode of wheezing and dyspnea

• RSV antigen detected by ELISA

• parents signed informed consent.

Exclusion Criteria:

• infants with chronic lung disease

• cardiac disease

• other chronic conditions.