Overview

Acute Application of Pegvisomant and Octreotide in Acromegaly

Status:
Completed
Trial end date:
2008-03-01
Target enrollment:
Participant gender:
Summary
The purpose of the study is to investigate the efficacy of an acute additional application of the somatostatin analogue octreotide 100µg s.c. or the dopamine agonist cabergoline 0.5mg p.o. to the receptor antagonist pegvisomant during a 6 or 9 hour profile on reducing endogenous growth hormone in patients with acromegaly on stable pegvisomant therapy.
Phase:
Phase 4
Details
Lead Sponsor:
Ludwig-Maximilians - University of Munich
Treatments:
Cabergoline
Dopamine
Dopamine Agonists
Octreotide
Somatostatin