Acute Cholecystitis - Early Laparoscopic Surgery Versus Antibiotic Therapy and Delayed Elective Cholecystectomy
Status:
Completed
Trial end date:
2010-12-01
Target enrollment:
Participant gender:
Summary
Acute cholecystitis is frequent in the elderly, or in patients with gall stones. Most cases
of severe or recurrent cholecystitis need surgery as final therapy. Today, the performed
procedure in most cases for cholecystectomy in the western world is laparoscopic
cholecystectomy. Only in some cases an open surgery has to be performed. Unclear is, what
time point is best, concerning outcome and morbidity of the patient, immediate surgery or
initial conservative therapy using antibiotics and symptomatic therapy with cholecystectomy
later on. Today the performed procedure is mainly chosen by the fact, what doctor sees the
patient first, surgeon or gastroenterologist. This study is performed to evaluate if one
therapy is superior.
Phase:
Phase 3
Details
Lead Sponsor:
Heidelberg University
Collaborator:
Bayer
Treatments:
Anti-Bacterial Agents Antibiotics, Antitubercular Moxifloxacin Norgestimate, ethinyl estradiol drug combination