Overview
Acute Maternal Hyperoxygenation for Fetal Transposition of the Great Arteries (TGA)
Status:
Recruiting
Recruiting
Trial end date:
2022-03-31
2022-03-31
Target enrollment:
0
0
Participant gender:
Female
Female
Summary
This prospective study will examine whether transient maternal hyperoxygenation is useful as a diagnostic test to more accurately detect TGA patients with poor vs. good neonatal intra-cardiac mixing of blood, based on the in-utero response to oxygen exposure.Phase:
N/AAccepts Healthy Volunteers?
NoDetails
Lead Sponsor:
The Hospital for Sick Children
Criteria
Inclusion Criteria:- Fetus with simple TGA +/- small VSD
- Intention of active postnatal management after birth
Exclusion Criteria:
- Fetus with complex form of TGA
- Significant fetal arrhythmia
- Major non-cardiac lesions
- Maternal contraindications for fetal MRI