Acute Myocardial Necrosis and Depression: Antiplatelet Effect of Reuptake Inhibition of Serotonin
Status:
Terminated
Trial end date:
2016-02-01
Target enrollment:
Participant gender:
Summary
Primary purpose:
To evaluate the evolution in time of the antiaggregant platelet effect of sertraline (SSRI)
compared to placebo in depressive patients with ACS (Acute Coronary Syndrome) and treated as
recommended by a double antiplatelet therapy, aspirin and clopidogrel.
Hypothesis:
The benefits of SSRIs observed in depressive patients with ACS are related to an antiplatelet
effect.
Phase:
Phase 4
Details
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Collaborators:
ACTION Group – www.action-cœur.org Action Research Group