Overview

Acute Pain Management in Patients on Opioid Replacement Therapy

Status:
Active, not recruiting
Trial end date:
2023-11-01
Target enrollment:
Participant gender:
Summary
This is an outpatient randomized within subject placebo-controlled human laboratory investigation of analgesia (as assessed with quantitative sensory testing; QST) from ketamine alone and in combination with hydromorphone in buprenorphine maintained participants. The goals of this project are to characterize the analgesic, subjective, and physiologic effects of ketamine combined with hydromorphone in patients on buprenorphine maintenance for opioid use disorder.
Phase:
Phase 1
Details
Lead Sponsor:
University of California, San Francisco
Treatments:
Buprenorphine
Hydromorphone
Ketamine