Acute Response of Iloprost Inhalation Using the Breelib Nebulizer in Pulmonary Arterial Hypertension
Status:
Completed
Trial end date:
2018-10-24
Target enrollment:
Participant gender:
Summary
Primary objective
• To evaluate the effect of rapid inhalation of 2.5μgiloprost using the Breelib nebulizer on
pulmonary vascular resistance (PVR) in patients with pulmonary arterial hypertension
Secondary objectives
- To evaluate the effect of rapid iloprost inhalation using the Breelib nebulizer on mean
pulmonary arterial pressure (mPAP), cardiac output (CO), cardiac index (CI), systemic
blood pressure, arterial oxygen saturation, heart rate, and pulmonary arterial wedge
pressure (PAWP).
- To evaluate the safety and tolerability of the rapid iloprost inhalation using the
Breelib nebulizer.