Addiction Treatment in Russia: Oral vs. Naltrexone Implant

• Status: Completed
• Trial end date: 2010-11-04
• Target enrollment: 0
• Participant gender: All

Summary

Heroin addiction is a growing problem in Russia; individuals who enter heroin addiction treatment often relapse. Therefore, effective heroin addiction treatments are necessary to prevent relapse. The purpose of this study is to compare oral naltrexone with a naltrexone implant that provides opioid blockade for two months in preventing relapse to heroin addiction in St. Petersburg, Russia.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Pennsylvania
• Collaborators: Leningrad Addiction Treatment & Research Center, Leningrad Region, Russia; National Institute on Drug Abuse (NIDA); St. Petersburg State Pavlov Medical University
• Treatments: Naltrexone

Criteria

Inclusion Criteria:

• Current opioid dependence

• Recently completed opioid detoxification

Exclusion Criteria:

• Serious medical or psychiatric condition requiring immediate hospitalization or that would make participation in the study hazardous

• Planning to leave the study area within the 12 months following study entry

• Imminent incarceration

• Pregnancy