Adding Magnesium Sulfate to Bupivacaine for Ilioinguinal and Iliohypogastric Nerve Block

• Status: Completed
• Trial end date: 2020-04-21
• Target enrollment: 0
• Participant gender: Male

Summary

Regional block of ilioinguinal and iliohypogastric (IIIH) nerves has been applied to provide postoperative analgesia after inguinal hernia repair. Magnesium sulfate (MgSo4) blocks N-methyl-d-aspartate receptors, and that is why, it was used as an adjuvant to the local anesthetic (LA) in different anesthetic approaches. Although the prolongation in postoperative duration resulting from the addition of MgSO4 to LA was significant in some literature studies, it was insignificant in others. This study was designed to investigate the adjunctive effect of MgSo4 when added to bupivacaine for IIIH blockade on the postoperative analgesic duration as a primary outcome and on the verbal rating scale (VRS) scores, analgesic consumption, and hemodynamics as secondary outcomes.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Abdelrady S Ibrahim, MD
• Treatments: Magnesium Sulfate

Criteria

Inclusion Criteria:

• Adult male

• American Society of Anesthesiologists physical status I or II

Exclusion Criteria:

• Patients with body mass index greater than or equal to 35 kg/m2

• allergy to the study drugs

• on chronic analgesics or drug containing magnesium