Adding MgSO4 to Epidural Levobupivacaine in CS for Patients With Preeclampsia

• Status: Completed
• Trial end date: 2017-01-01
• Target enrollment: 0
• Participant gender: Female

Summary

This study aims at evaluating the effect of adding magnesium sulphate epidurally as an adjunct to levobupivacaine on the quality of anesthesia and perioperative pain relief in patients with preeclampsia undergoing elective caesarian section (CS).

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mohamed Sayed Abdelhafez
• Treatments: Bupivacaine; Levobupivacaine; Magnesium Sulfate

Criteria

Inclusion Criteria:

• Pregnant women with preeclampsia undergoing elective CS.

Exclusion Criteria:

• Age < 20 or > 35 years.

• Height < 150 or > 180 cm.

• Body mass index (BMI) > 35 kg/m2.

• Active labor.

• Multifetal pregnancy.

• Fetal distress.

• Medical conditions complicating pregnancy.

• HELLP syndrome.

• Thrombocytopenia.

• Hepatic or renal impairment.

• Pulmonary edema or cyanosis.

• Placenta previa.

• Vaginal bleeding or placental abruption.

• Contraindication for central neuraxial block.

• History of adverse reaction to any study medication.

• History of analgesic use.

• Magnesium therapy.

• Chronic pain syndrome.

• Presence of communication difficulties preventing reliable assessment.

• Refusal to undergo regional anesthesia.