Adding Nalbuphine for Control of Intrathecal Morphine Pruritus

• Status: Recruiting
• Trial end date: 2021-03-01
• Target enrollment: 0
• Participant gender: All

Summary

Intrathecal morphine causes intense itching which is very bothersome. Nalbuphine antagonizes this effect when given intravenously. This trial is to find out if nalbuphine added to intrathecal morphine has an effect on morphine related pruritus while still maintaining adequate analgesia.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Minia University
• Treatments: Morphine; Nalbuphine

Criteria

Inclusion Criteria:

• Male and female patients.

• Age 18-80yrs.

• Elective major abdominal surgery under general anesthesia.

Exclusion Criteria:

• Refusal to participate.

• Skin or systemic disease with itching. Any condition which precludes performing spinal injection