Addition of Naltrexone to Methadone Taper

• Status: Completed
• Trial end date: 2006-07-01
• Target enrollment: 0
• Participant gender: All

Summary

There is a continuing search for more effective opiate detoxification treatments. This study's purpose is to investigate the effects of adding very low doses of naltrexone to a methadone tapering treatment in opioid dependent individuals.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Institute on Drug Abuse (NIDA)
• Treatments: Methadone; Naltrexone

Criteria

Inclusion Criteria:

• Current DSM-IV diagnosis of opiate dependence

• Reads and understands English

Exclusion Criteria:

• Serious medical disorders (e.g., uncontrolled hypertension, acute or chronic active hepatitis, kidney failure, uncontrolled diabetes)

• Psychiatric conditions that require intensive services (e.g., depression with suicidal ideation, psychosis)

• Mental retardation or other disorder that might limit ability to give informed consent

• Pregnant