Addition of Prednisolone and Heparin in Patients Undergoing IVF With Failed IVF Cycles

• Status: Completed
• Trial end date: 2016-07-01
• Target enrollment: 0
• Participant gender: Female

Summary

The addition of heparin and prednisolone increases pregnancy outcome parameters in women undergoing In Vitro Fertilisation (IVF) with failed IVF cycles.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National and Kapodistrian University of Athens
• Treatments: Calcium heparin; Dalteparin; Heparin; Heparin, Low-Molecular-Weight; Methylprednisolone; Methylprednisolone acetate; Methylprednisolone Hemisuccinate; Prednisolone; Prednisolone acetate; Prednisolone hemisuccinate; Prednisolone phosphate

Criteria

Inclusion Criteria:

• personal history of ≥2 failed IVF/ICSI cycles

• age <45 years

• availability of fresh ejaculate sperm for IVF/ICSI procedures

• confirmation of normal uterine cavity

• presence of good quality (Grade I or II) embryos for transfer

Exclusion Criteria:

• endocrine disorders

• immune disorders

• coagulation disorders