Adenosine Contrast CorrELations in Evaluating RevAscularizaTION
Status:
Recruiting
Trial end date:
2022-01-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to compare FFR measurements done with adenosine to FFR
measurements done with contrast, where the contrast is injected using the ACIST CVi automated
contrast injector.
The ACCELERATION study will support a safer approach to FFR for patients by potentially
reducing toxic drug exposure (adenosine). The 2 main objectives of the study are:
1. Perform a methods comparison between cFFR and the reference standard aFFR, where cFFR is
performed using an automated injector with a standardized volume and rate of delivery of
contrast with known osmolality.
2. Evaluate the association between final post-PCI FFR and long-term clinical outcomes. The
long-term clinical outcomes will include TVR and composite MACE (death, MI, and TVR) at
30 days and 1 year.