Adenosine Versus Verapamil for Management of Supraventricular Tachycardia Post- Coronary Artery Bypass Grafting
Status:
Completed
Trial end date:
2020-11-22
Target enrollment:
Participant gender:
Summary
This prospective study was conducted in 268 patients aged from 65-70 years posted for
coronary artery bypass grafting. Patients were randomly allocated to either adenosine or
verapamil(control) groups. In the adenosine group, patients received IV adenosine 6 mg bolus
then wait 2 minutes, if it failed to return to sinus rhythm then another 12 mg IV bolus of
adenosine was administered, if supraventricular tachycardia persisted then the patient was
shifted to verapamil. In verapamil group, patients received IV verapamil 5mg bolus slowly
over 2 minutes followed by a second IV bolus dose of 5 mg ,10 minutes after the initial dose
in case of persistence of supraventricular tachycardia (SVT). If SVT persisted, the patient
was shifted to adenosine. The efficacy of the study drug, ICU stay length, systolic blood
pressure, hospital- stay length, duration of extubation, the total dose of the study drug
used, the total cost of the study drugs and the incidence of adverse events were recorded.