Overview

Adenosine and Magnesium Sulphate as Adjuvants for PECS Block.

Status:
Completed

Trial end date:
2017-07-22

Target enrollment:
0

Participant gender:
All

Summary

Pectoral nerve block (PECS) has been used for post-operative pain relief in patients undergoing breast surgery. It has been shown that adenosine has an effect on pain modulation. Magnesium sulphate has been used as an adjuvant to local anaesthetics in many nerve block techniques. We hypothesised that adenosine may affect the PECS block quality. We aimed to compare the effect of adding adenosine to the local anaesthetic and compare its effect to magnesium sulphate when used for PECS block.

Phase:

N/A

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Menoufia University

Treatments:

Adenosine
Bupivacaine
Magnesium Sulfate

Criteria

Inclusion Criteria:

- Patients scheduled for modified radical mastectomy with axillary clearance surgery ASA
classes I, II, and III patients were included in the study

Exclusion Criteria:

- 1) contraindications for regional anesthesia such as coagulopathy, local infection and
fungating breast cancer, 2) history of allergy to the medications used in the study,
3) patient with history of drug abuse, 4) previous breast surgery except for
diagnostic biopsies, 5) history of treatment for a chronic pain condition, 6)
psychiatric disorder.