Adherence, Efficacy and Safety of an Insulin Protocol in the Critically Ill: A Prospective Observational Study

• Status: Completed
• Trial end date: 2002-12-01
• Target enrollment: 0
• Participant gender: All

Summary

There is a growing body of evidence in the literature regarding the adverse effects of hyperglycemia in critically ill patients. To target and maintain better blood glucose regulation we implemented an insulin protocol with target blood glucose levels between 81-110 mg/dL.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Ghent
• Treatments: Insulin; Insulin, Globin Zinc

Criteria

Inclusion Criteria:

• Surgical or medical critically ill patients

• An expected ICU-stay of more than 72 hours

• Age > 16 years

• Need for insulin therapy

• Patients must have an arterial line

Exclusion Criteria:

• Patients who did not respond to the inclusion criteria

• Patients with diabetic ketoacidosis

• Cardiac surgical patients

• Patients transferred from other hospitals

• Other study enrollment