Adjunctive Oral Systemic Vitamin E Therapy on Salivary Nitric Oxide Level in Patients With Erosive Oral Lichen Planus
Status:
Completed
Trial end date:
2023-03-05
Target enrollment:
Participant gender:
Summary
Oral lichen planus (OLP) is a chronic inflammatory disease affecting the skin, mucous
membranes,s and rarely scalp and nails. It is a T-cell-mediated autoimmune disease.
Traditional treatment for OLP is topical steroids commonly used to treat mild to moderately
symptomatic lesions. Recent treatment modalities for oral lichen planus include
micronutrients such as antioxidants including vitamin E that modify the immune system
function. The aim of this study is to evaluate the efficacy of adjunctive oral systemic
vitamin E therapy on salivary nitric oxide levels in patients with erosive oral lichen
planus.