Adjunctive Probiotics in Chronic Periodontitis

• Status: Completed
• Trial end date: 2018-10-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will assess clinical and microbiological efficacy of probiotics and antibiotics in patients of chronic periodontitis as an adjunctive to scaling and root planing (SRP) in reducing bacterial count and in improving clinical periodontal parameters over the period of 12 weeks.Also the comparison between these adjunctives will be made for clinical assessment clinical periodontal parameters will be taken .these parameters plaque index (PI), gingival index (GI), clinical attachment loss (CAL) and pocket probing depth (PPD) for microbiological assessment plaque sample will be taken, DNA will be extracted and then sample will be processed through quantitative polymerase chain reaction (qPCR) for quantitative analysis of bacterial count of porphyromonas gingivalis.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Ziauddin Hospital
• Treatments: Amoxicillin; Metronidazole

Criteria

Inclusion Criteria:

• Patients with clinically diagnosed chronic periodontitis with a pocket depth of ≥4mm.

• Patients with age ≥30 years.

Exclusion Criteria:

• Handicapped patients who are physically or mentally unable to maintain their oral hygiene.

• Pregnant and lactating females.

• Patients with habits of smoking, chewing tobacco and alcohol consumption.

• Patients on local or systemic antibiotic treatment.

• Patients with any systemic diseases.

• Patients with the history of any periodontal therapy within last 6 months.

• Patients undergoing orthodontic treatment.