Adjuvant Chemotherapy in Patients With Lymph Node Metastasis After Radical Surgery in Cervical Cancer

• Status: Unknown status
• Trial end date: 2015-01-01
• Target enrollment: 0
• Participant gender: Female

Summary

Purpose Primary endpoint

• To evaluate the 3-year disease free survival Second endpoints

• To evaluate the 3-year & 5-year overall survival To analyze the toxicity and the quality of life

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Korean Gynecologic Oncology Group
• Treatments: Cisplatin; Paclitaxel

Criteria

Inclusion Criteria:

• cervical cancer stage Ia2-IIa

• histology; squamous, adeno, adenosquamous subtype

• age; 20∼70 years

• performance status; GOG 0∼2

• no medical illness

• hematologic, renal, hepatic function; normal

• grossly no residual disease

• histologically confirmed lymph nodes metastases

• no parametrial extension and negative resection margin

• number of retrieved lymph nodes; ≥ 20

Exclusion Criteria:

• patients with grade 2 peripheral neuropathy

• patients with uncontrolled infection