Adjuvant Effect of Dexmedetomidine in Ultrasound (USG) Guided Transvers Abdominis Plane Block

• Status: Withdrawn
• Trial end date: 2015-11-01
• Target enrollment: 0
• Participant gender: All

Summary

A total of 60 adult patients American Society of Anesthesiologists physical status I,II, III were randomized to Group B (n = 30) receiving TAP block with 0.25% bupivacaine and Group D (n = 30) with 0.5 mcg/kg dexmedetomidine added to 0.25 % bupicavaine followed by general anaesthesia. Total local anaesthetic volume was standardised with 20 ml each sides of the abdomen. Hemodynamic responses to surgical incision and intraoperative fentanyl consumption were noted. Visual analog scale (VAS) scores were assessed on the emergence, at 1, 2, 3, 4, 5, 6 and 24 h. Time to first rescue analgesic (when VAS ≥4 cm or on demand), duration of postoperative analgesia, incidence of postoperative nausea-vomiting were also noted.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Kırıkkale University
• Treatments: Bupivacaine; Dexmedetomidine

Criteria

Inclusion Criteria:

• The patients undergoing laparascopic cholecystectomy

Exclusion Criteria:

• Story of allergy to bupivacaine and dexmedetomidine

• The surgery preceeded to laparatomy

• Recent abdominal operation history