Adjuvant Entecavir or Tenofovir for Postoperative HBV-HCC

• Status: Recruiting
• Trial end date: 2022-12-30
• Target enrollment: 0
• Participant gender: All

Summary

This study aims to compare the effect of antiviral therapy with entecavir or tenofovir for hepatitis B virus-related hepatocellular carcinoma after radical hepatectomy. Included patients will randomly divide into two groups.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Guangxi Medical University
• Treatments: Entecavir; Lamivudine; Tenofovir

Criteria

Inclusion Criteria:

• Underwent open hepatic resection.

• Diagnosis of HCC was confirmed by imageological examination with or without AFP.

• HBsAg (+).

• Child-Pugh A liver function.

Exclusion Criteria:

• Anti-HCV(+)

• Diagnosis of HCC was not confirmed by histopathological examination of surgical samples after surgery.