Overview

Adjuvant Erlotinib Intercalating Chemotherapy or Adjuvant Chemotherapy Alone in NSCLC With Common EGFR Mutation

Status:
Withdrawn
Trial end date:
2020-11-01
Target enrollment:
Participant gender:
Summary
This study will be performed as a local multicenter, randomized, phase III clinical study. It will compare the adjuvant chemotherapy in Stage IB-IIIA NSCLC with common EGFR mutation (Exon 19 deletion or L858R) who underwent total resection and the Erlotinib-Intercalation adjuvant chemotherapy with the chemotherapy alone. The patients will be randomly assigned to the Intercalation combination chemotherapy regimen and the chemotherapy alone regimen at the ratio of 1:1. The treatment regimen of each arm is as follows.
Phase:
Phase 3
Details
Lead Sponsor:
Yonsei University
Treatments:
Cisplatin
Erlotinib Hydrochloride
Pemetrexed
Vinorelbine