Adjuvants With Intrathecal Bupivacaine for Postoperative Analgesia

• Status: Not yet recruiting
• Trial end date: 2024-12-30
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to compare the postoperative analgesic effect of intrathecal dexmedetomidine combined with bupivacaine and midazolam combined with bupivacaine in high tibial osteotomy.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Assiut University
• Treatments: Bupivacaine; Dexmedetomidine; Midazolam

Criteria

Inclusion Criteria:

• Adult patients aged 18-60 years.

• Gender: Both males and females.

• Scheduled patients for High tibial osteotomy under spinal anesthesia.

• American Society of Anesthesiologists (ASA) physical status: I and II

Exclusion Criteria:

• Patient refusal

• Allergy to the studied drugs.

• Patients with contraindications to spinal anesthesia.

• Patients with advanced decompensated cardiac, respiratory,renal or hepatic diseases

• Coagulopathy or thrombocytopenia

• CNS diseases as epilepsy, stroke or psychiatric illness.