Administration of Dexmedetomidine Guided by Entropy/SPI Reduce
Status:
Unknown status
Trial end date:
2017-10-01
Target enrollment:
Participant gender:
Summary
Dexmedetomidine, a selective alpha2-adrenergic agonist is known to reduce propofol and opioid
requirements due to its sedative and analgesic properties. However, until now, there has been
studies based on indirect measures such as hemodynamics. Entropy shows to quantify the level
of consciousness by EEG and Surgical pleth index(SPI) allows to predict the effect of pain
stimuli and analgesic therapy by the index of the nociception-anti-nociception balance. The
investigators analyzed quantitatively the requirements of propofol and remifentanil under
continuous infusion of dexmedetomidine when using entropy and SPI.