Alcohol, Behavior, and Brain Imaging

• Status: Completed
• Trial end date: 2019-05-30
• Target enrollment: 0
• Participant gender: All

Summary

To evaluate the relationship of extraversion to both the acute subjective and behavioral effects of alcohol, and the neural reactivity to the anticipation of reward.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Chicago
• Treatments: Ethanol

Criteria

Inclusion Criteria:

• 21-29 years old

• 7-30 alcoholic drinks per week (as reported on PHQ or TLFB)

• At least one binge episode (4 for females/5 for males) per month

• No 'flushing' reaction to alcohol

• Females must be on birth control or in the beginning of follicular phase (1-14 days after start of menstruation)

• BMI 19-26

• High school education or greater, fluent in English

• No night shift work

• No current or past year Axis I psychiatric disorder including drug/alcohol dependence

• No current psychopharmacological treatment

• No lifetime ADHD or prescription for ADHD medication

• No abnormal EKG, cardiovascular illness, high blood pressure

• No medical condition or pharmacological treatment for which alcohol is contraindicated

• Not pregnant, lactating, or planning to become pregnant

• Smoke <6 cigarettes per day

• No previous participation in studies that have used the Stop Task (except IDAC) o Previous Stop Task studies: GOI, CAP, STEM, JAM, MACI, PAC, CAM