Overview Aldosterone and the Metabolic Syndrome Status: Completed Trial end date: 2013-09-01 Target enrollment: Participant gender: Summary The purpose of this study is to determine the effects of mineralocorticoid receptor (MR) antagonism and renin inhibition on glucose metabolism in humans. Phase: Phase 1 Details Lead Sponsor: Vanderbilt UniversityVanderbilt University Medical CenterTreatments: HydrochlorothiazideInsulinLactitolSpironolactone