Alendronate in the Prevention of Collapse of Femoral Head in Non-Traumatic Osteonecrosis

• Status: Unknown status
• Trial end date: 2008-06-01
• Target enrollment: 0
• Participant gender: All

Summary

To determine the cumulative incidence of total hip replacement, time to event after treatment with Fosamax or placebo during the study peroid

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Kaohsiung Medical University Chung-Ho Memorial Hospital
• Collaborators: Merck Sharp & Dohme Corp.; National Cheng-Kung University Hospital; National Taiwan University Hospital
• Treatments: Alendronate

Criteria

Inclusion Criteria:

• osteonecrosis of femoral head

• be able to provide singed informed consent

Exclusion Criteria:

• prior bisphosphonate use

• pregnant or lactating woman

• bilateral hip replacement