Overview

Alirocumab and Reverse Cholesterol Transport

Status:
Completed
Trial end date:
2018-07-30
Target enrollment:
Participant gender:
Summary
Alirocumab is an injectable treatment for elevated blood cholesterol. The hypothesis of this study is that it also increases cholesterol excretion from the body into the stool, a process sometimes called reverse cholesterol transport. A cholesterol metabolic study will be done before and after 6 weeks of alirocumab treatment. If alirocumab increases reverse cholesterol transport, it is possible that this action provides additional protection from cardiovascular disease.
Phase:
Phase 1
Details
Lead Sponsor:
Washington University School of Medicine
Treatments:
Antibodies, Monoclonal