Allergic Inflammation in Rhinitis Patients Following Nasal Allergen Challenge
Status:
Completed
Trial end date:
1997-04-01
Target enrollment:
Participant gender:
Summary
Allergic rhinitis is a common condition caused by inflammation of nasal mucosa. The study was
performed to gain information on this inflammation, including effect of intranasal
corticosteroid treatment hereupon and potential influence on the lower airways, ie asthma.
The study was randomised, placebo-controlled double-blind in patients, monoallergic to
grasspollen, presenting symptoms of rhinitis and asthma during season.
Treatment,ie intranasal corticosteroid or placebo, were given four weeks. After two weeks of
treatment intranasal allergen challenge was performed. Measurements were performed during the
full study period.
The study was performed out of pollen season.