Overview

Allogeneic HCT With HLA-matched Donors : a Phase II Randomized Study Comparing 2 Nonmyeloablative Conditionings

Status:
Completed
Trial end date:
2012-03-01
Target enrollment:
Participant gender:
Summary
The present project aims at comparing two nonmyeloablative regimens currently used in 2 major HCT centers in the US for patients with HLA-matched related or unrelated donor: the one from the Seattle group consisting of 2 Gy TBI with fludarabine (90 mg/m²) versus the one from the Stanford group combining 8 Gy TLI with ATG.
Phase:
Phase 2
Details
Lead Sponsor:
University Hospital of Liege
University of Liege
Collaborators:
Katholieke Universiteit Leuven
KU Leuven
Maastricht University Medical Center
Treatments:
Fludarabine
Fludarabine phosphate
Thymoglobulin