Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia
Status:
Recruiting
Trial end date:
2026-04-01
Target enrollment:
Participant gender:
Summary
The ALL SCTped 2012 FORUM is a multinational, multi-centre, controlled, prospective phase III
study for the therapy and therapy optimisation for children and adolescents with ALL in
complete morphological remission (CR, less than 5% bone marrow blasts, no blasts in
cerebrospinal fluid, no other extramedullary leukemia), who have an indication for HSCT with
a myeloablative conditioning regimen.
The stratification of patients in first and following remissions according to the individual
transplantation modalities rests upon an indication for allogeneic HSCT and the availability
of a suitable donor within the individual transplantation groups.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
St. Anna Kinderkrebsforschung
Collaborators:
ALL SCTped Forum ALL-BFM Study Group Assistance Publique - Hôpitaux de Paris Australian & New Zealand Children's Haematology/Oncology Group Dutch Childhood Oncology Group European Society for Blood and Marrow Transplantation Swiss Pediatric Oncology Group