Alpha-Lipoic Acid in Preventing Peripheral Neuropathy in Patients Receiving Chemotherapy for Cancer
Status:
Completed
Trial end date:
2014-04-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer
cells, either by killing the cells or by stopping them from dividing. Chemoprotective drugs,
such as alpha-lipoic acid, may protect normal cells from the side effects of chemotherapy.
Alpha-lipoic acid may also prevent damage to nerves that carry information to and from the
brain and spinal cord to the rest of the body. It is not known whether alpha-lipoic acid is
more effective than placebo in preventing peripheral neuropathy.
PURPOSE: This randomized phase III trial is studying alpha-lipoic acid to see how well it
works compared to placebo in preventing peripheral neuropathy in patients receiving
chemotherapy for cancer.