Overview

Alpha-lipoic Acid in Diabetic Patients With Ischemic Cardiomyopathy

Status:
Completed
Trial end date:
2024-02-01
Target enrollment:
0
Participant gender:
All
Summary
The aim of this study is to investigate the effect of alpha-lipoic acid on inflammatory markers and cardiac fibrosis markers in diabetic patients with Ischemic Cardiomyopathy.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Damanhour University
Treatments:
Thioctic Acid
Criteria
Inclusion criteria:

- Type 2 diabetes with a history of CAD.

- LV ejection fraction (LVEF) ≤40%.

- Ischemic heart failure patients with NYHA grade II-IV.

Exclusion criteria:

- Type 1 diabetes.

- Severe CKD with GFR ≤ 15 ml/min/1.73m^2.

- Severe liver disease.

- Thyroid disorders.

- Acute febrile illness.

- Autoimmune disorders or connective tissue disorders.