Alpha1 Antitrypsin Aerosol Therapy in Cystic Fibrosis
Status:
Terminated
Trial end date:
2005-10-01
Target enrollment:
Participant gender:
Summary
The hypothesis being tested is that inhibition of the enzyme known as elastase in the airways
of patients with cystic fibrosis will help decrease the number of bacteria. Alpha1
antitrypsin, an elastase inhibitor, will be given to patients with cystic fibrosis by aerosol
therapy twice in 1 day and sputum will be collected to measure the density of bacteria