Alprazolam as Conscious Sedation for Upper Gastrointestinal Endoscopy
Status:
Completed
Trial end date:
2013-01-01
Target enrollment:
Participant gender:
Summary
Diagnostic esophagogastroduodenoscopy is an uncomfortable and stressful procedure for most of
the patients. Various methods are available for sedation during this procedure. Because of
some side effects related to intravenous administration of sedatives, oral administration of
these drugs is under attention. Alprazolam is a benzodiazepine which is used mainly in
treatment of anxiety. Hence, we determine the efficacy of oral and sublingual alprazolam as
for sedation during this procedure. We hypothesize that sublingual alprazolam is more
effective than that oral form and both forms more effective than placebo in reducing anxiety
and pain/discomfort related to the procedure.