Overview

Alternation in the Human Microbiome With Commonly Used Topical Medications

Status:
Recruiting
Trial end date:
2026-09-28
Target enrollment:
Participant gender:
Summary
The global aim of this study is to investigate how the human microbiome changes from baseline with commonly used topical medications such as topical antifungals, low to mid potency topical steroids and emollients. The specific aims are as follows: 1. Investigate whether ketoconazole cream, a commonly used topical antifungal, causes alterations in the human skin microbiome with short-term use. 2. Investigate whether desonide 0.05 % ointment, a commonly used low potency topical steroid, alters the human microbiome with short-term use.
Phase:
Phase 1
Details
Lead Sponsor:
University of California, Davis
Treatments:
Desonide
Ketoconazole