Alvimopan and Ileus in PSF

• Status: Completed
• Trial end date: 2019-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to determine with Alvimopan reduces the incidence of post operative ileus in patients who undergo posterior spinal fusion.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Washington University School of Medicine
• Collaborators: Barnes-Jewish Hospital; Orthopedic Research and Education Foundation
• Treatments: Alvimopan

Criteria

Inclusion Criteria:

• adult patients undergoing elective PSF of at least 5 levels and/or fixation to pelvis

Exclusion Criteria:

• pregnant women

• ischemic heart disease

• chronic liver or renal disease

• prior bowel resection

• presence of colostomy or ileostomy

• gastroparesis

• complete bowel obstruction

• inflammatory bowel disease (ulcerative colitis or Crohn's disease).