Alvocidib, Cytarabine, and Mitoxantrone in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
Status:
Completed
Trial end date:
2012-09-01
Target enrollment:
Participant gender:
Summary
This randomized phase II trial is studying two different schedules of alvocidib to compare
how well they work when given together with cytarabine and mitoxantrone in treating patients
with newly diagnosed acute myeloid leukemia. Drugs used in chemotherapy, such as alvocidib,
cytarabine, and mitoxantrone, work in different ways to stop the growth of cancer cells,
either by killing the cells or by stopping them from dividing. It is not yet known which
schedule of alvocidib is more effective when given together with cytarabine and mitoxantrone
in treating patients with acute myeloid leukemia.