Alvocidib, Oxaliplatin, Fluorouracil, and Leucovorin Calcium in Treating Patients With Advanced Solid Tumors
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
This phase I trial is studying the side effects and best dose of alvocidib when given
together with oxaliplatin, fluorouracil, and leucovorin calcium in treating patients with
advanced solid tumors. Drugs used in chemotherapy, such as alvocidib, oxaliplatin,
fluorouracil, and leucovorin calcium, work in different ways to stop tumor cells from
dividing so they stop growing or die. Alvocidib may also make tumor cells more sensitive to
chemotherapy. Combining more than one chemotherapy drug may kill more tumor cells.